SAAD Digest
March 2024
Volume: 40
Issue: 1
Title: Dental treatment for a 15-year-old patient with Nicolaides-Baraitser Syndrome, under intravenous sedation with midazolam: a case report
Author(s): J. Coomar
Abstract:
A 15-year-old male with Nicolaides-Baraitser Syndrome (NCBRS), presented for a routine examination complaining of lower left tooth pain. NCBRS is a very rare genetic condition caused by mutations in the SMRCA2 gene, affecting chromatin remodelling where patients can exhibit delayed eruption of permanent teeth, spaced dentition and hypodontia.1 He also has a severe learning disability, heart murmur, ADHD, psoriasis, asthma (mild), scoliosis and limited speech.
He exhibited severe crowding, an anterior open bite, multiple retained deciduous teeth, a fractured upper left central incisor and a grossly carious upper right deciduous second molar. An orthodontic opinion was sought and the extraction of all deciduous teeth was advised. After discussing treatment options with his parent, intravenous sedation was chosen due to the patient’s challenging co-operation for extractions. The treatment was completed over three appointments under intravenous sedation, with an operative score of three and a general anaesthetic was avoided.
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Articles from Digest 40(1)