SAAD Digest 

March 2025
Volume: 41
Issue: 1
DOI: 10.63507/QATP4875

Title: Remimazolam as a sedative for dental procedures: a case series

Author(s):  A M. Liow, N. Akuffo, X H. Yeo, S. Clough.

Abstract: 

Within dentistry, pharmacological support may be required to facilitate the delivery of dental treatment for patients with additional emotional or physical needs. The most common drug of choice for intravenous sedation in dentistry is midazolam due to its efficacy and established safety record. However, the introduction of remimazolam offers a promising alternative with a similar mechanism of action but with a faster onset and recovery, which can be advantageous for patients and service providers. 

We present a series of four cases using remimazolam as an intravenous sedative for dental procedures, with varied medical and dental histories and an age range from 19 to 76 years old. We describe the administration regimen, with variation depending on the patient’s age, co-morbidities and individual circumstances. Patients’ pre- and post-operative haemodynamic measures and quality of sedation in these different circumstances were also reported.

Within the limitation of the case series, remimazolam was shown to be an effective sedative agent for dental procedures without any adverse events. Our experience offers promising findings, in particular demonstrating rapid recovery of patients. However, larger scale studies are welcomed in dentistry to further develop the related evidence base.

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Articles from Digest 41(1)